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Novel Insights into the Regulatory Architecture of CD4+ T Cells in Rheumatoid Arthritis

Figure 2

Building of functional-based networks for M9 and M12 CD4+ gene expression modules using biological knowledge.

A: Functional-based network obtained from the immunologically enriched M9 gene expression module where 15 genes display a connected network. B: Functional-based network obtained from the immunologically enriched M12 gene expression module, which shows a complex network structure with different subnetworks involving 247 interconnected genes.

Figure 2

doi: https://doi.org/10.1371/journal.pone.0100690.g002