Efficient Induction of Apoptosis by Wee1 Kinase Inhibition in Hepatocellular Carcinoma Cells
Figure 3
Wee1 kinase is expressed in moderately to poorly differentiated HCC.
A-C, Wee1 kinase was stained with anti-Wee1 antibodies in surgically resected HCC samples (▾ HCC lesion). Anti-Wee1 antibody staining revealed mostly nuclear localization in Wee1 kinase-positive cells. The magnification is 40 x (A), 100 x (B), or 200 x (C). Scale bars = 200 µm. D, Wee1 kinase is expressed in moderately to poorly differentiated HCC. A chi-square test revealed significant differences (p = 0.0026). (NC; Non-cancerous lesion, Mod.; Moderately).