The In Vitro and In Vivo Antitumor Effects of Clotrimazole on Oral Squamous Cell Carcinoma
Figure 3
Clotrimazole induces G0/G1 cell cycle arrest in OSCC cells.
OSCC cells were exposed to various concentrations of clotrimazole (0, 30 and 40 µM) for 24 h. Cell cycle distributions were analyzed by flow cytometry with PI staining. *P<0.05, **P<0.01 as compared with the CAL27 control cells; # P<0.01 as compared with the SCC25 control cells; ‡P<0.01 as compared with the UM1 control cells.