Defective Apoptosis in Intestinal and Mesenteric Adipose Tissue of Crohn’s Disease Patients
Figure 5
Representative Western blot analyses and determination of Bax and Bcl-2 protein expression in the intestinal tissue (mucosa) of the Crohn’s disease group (ICD) and in the mesenteric adipose tissue (MAT) of the Crohn’s disease group (ACD), compared to the respective controls (IC and AC).
Decreased expression of Bax was observed in ICD group, compared to the control group (IC), and higher expression of Bcl-2, an anti-apoptotic protein, was observed in the MAT of Crohn’s disease (ACD) compared to the control group (AC). For illustration purposes, each band represents one patient. For ICD, n = 10; for ACD, n = 10; for IC, n = 8; and, for AC, n = 8, *p<0.05 vs control.