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Hp1404, a New Antimicrobial Peptide from the Scorpion Heterometrus petersii

Figure 4

Toxicity of Hp1404 in vitro and in vivo.

(A) Hemolytic activity of Hp1404 against human red blood cells. BmKn2 is a highly hemolytic antimicrobial peptide from the scorpion Mesobuthus martensii Karsch. (B) Cytotoxicities of Hp1404 against HFF, HEK293T and A375 cell lines. Cytotoxicity was measured by MTT assay. (C) Acute toxicity of Hp1404 to mice by intravenous injection.

Figure 4

doi: https://doi.org/10.1371/journal.pone.0097539.g004