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B-Ring-Aryl Substituted Luotonin A Analogues with a New Binding Mode to the Topoisomerase 1-DNA Complex Show Enhanced Cytotoxic Activity

Table 2

Quantification of the affinities of compounds 3ag for their binding sites and its correlation with their inhibitory activity.

Table 2

doi: https://doi.org/10.1371/journal.pone.0095998.t002