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Interaction of 6 Mercaptopurine with Calf Thymus DNA – Deciphering the Binding Mode and Photoinduced DNA Damage

Figure 6

Role of ionic strength.

To study the role of electrostatic effect on 6MP-DNA binding, NaCl was used. Maximum emission intensity plot of 6MP-DNA was plotted with increasing concentration of NaCl (0–70mM). Excitation wavelength was 280 nm. Increase in fluorescence intensity suggests for a possible electrostatic interaction between 6MP and CT-DNA.

Figure 6

doi: https://doi.org/10.1371/journal.pone.0093913.g006