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Interaction of 6 Mercaptopurine with Calf Thymus DNA – Deciphering the Binding Mode and Photoinduced DNA Damage

Figure 5

KI quenching experiment.

Stern-Volmer plot for fluorescence quenching of 6MP (50 μM) by KI in absence and presence of CT-DNA (100 μM). Quenching of 6MP fluorescent intensity was done using KI in absence and presence of CT-DNA and quenching constant was calculated in both the case. Difference in Ksv value was further used to investigate the binding mode of 6MP and DNA.

Figure 5

doi: https://doi.org/10.1371/journal.pone.0093913.g005