An EGFR/HER2-Bispecific and Enediyne-Energized Fusion Protein Shows High Efficacy against Esophageal Cancer
Figure 5
Effects of Ec-LDP-Hr-AE on the EGFR/HER2 signaling.
The expression of apoptosis related molecules (e.g. Caspase 3, Caspase 7 and PARP) and key molecules in the EGFR/HER2 signaling pathways (e.g. phosphorylated-EGFR, -HER2, -ERK, -p38MAPK, -JNK, -AKT) were determined by Western blot analysis. β-actin was served as a loading control.