Inhibition of Enterovirus 71 Replication by 7-Hydroxyflavone and Diisopropyl-Flavon7-yl Phosphate
Figure 2
Inhibition of EV71 3Cpro protease activity by FIP in vitro.
(A) Synthesis of FIP from HF by a simplified Atherton-Todd reaction. (B) Molecular docking model for FIP with viral 3Cpro. (C) Protease activity for EV71 3Cpro was noticeably inhibited by FIP (P<0.05). Standard deviations of three independent experiments are shown.