cAMP Signaling Prevents Podocyte Apoptosis via Activation of Protein Kinase A and Mitochondrial Fusion
Figure 6
Mitochondria fusion/fission was involved in podocyte apoptosis.
A: Mitochondria staining of podocytes treated with ARA or Mdivi. B: CCK-8 results from podocytes treated with ARA for the indicated time. Data were obtained from five independent experiments. C: Western blot of podocytes treated with ARA for the indicated time. D: CCKD-8 was performed using podocytes incubated with the indicated reagents. Data from five independent experiments are shown. E: Western blot of podocytes treated with the indicated reagents. F: Western blot of podocytes treated with PAN in the presence or absence of Mdivi-1. *: P<0.05 compared with control group, #: P<0.05 compared with PAN group, $: P<0.05 compared with pCPT+PAN group. pCPT: pCPT-cAMP.