DMH1, a Small Molecule Inhibitor of BMP Type I Receptors, Suppresses Growth and Invasion of Lung Cancer
Figure 3
DMH1 reduces A549 cell proliferation and induces cell death.
A549 cells were treated with DMH1 (3 and 5 µM) or DMSO for 48 hours and cell proliferation was determined by the sulforhodamine B (SRB) assay. (B) A549 cells were treated with DMH1 or DMSO for 72 hours, and cells were harvested for cell death assay using Trypan Blue staining. *: p-value is <0.05.