DMH1, a Small Molecule Inhibitor of BMP Type I Receptors, Suppresses Growth and Invasion of Lung Cancer
Figure 1
DMH1 inhibits basal Smad phosphorylation and transcription of Id genes in NSCLC cells.
Chemical structure of DMH1; (B) Western blotting for phosphorylated Smad1/5/8 in A549 cells treated with DMH1 at various concentrations (1, 3, and 5 µM); (C) QPCR results of Id1, 2 and 3 in A549 cells treated with DMH1 and vehicle DMSO. *: p-value is <0.05.