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Heterologous Expression of the Thiopeptide Antibiotic GE2270 from Planobispora rosea ATCC 53733 in Streptomyces coelicolor Requires Deletion of Ribosomal Genes from the Expression Construct

Figure 2

Phylogenetic tree based on 16S rRNA gene sequences of selected actinomycetes.

Neighbor-joining cladogram constructed in MEGA5 [44]; alignment of the sequences was done with CLUSTALW, bootstrap values (in percent) are calculated from 1000 resamplings and shown at the respective nodes for values >50%, the scale bar represents 0.02% sequence divergence. The tree is rooted to 16S rRNA from Bacillus cereus ATCC 14579.

Figure 2

doi: https://doi.org/10.1371/journal.pone.0090499.g002