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Temsirolimus Inhibits Proliferation and Migration in Retinal Pigment Epithelial and Endothelial Cells via mTOR Inhibition and Decreases VEGF and PDGF Expression

Figure 2

Proliferation of HUVEC and pRPE cells.

Inhibition of HUVEC (2A) and RPE cell (2B) proliferation after incubation with three different concentrations of temsirolimus over 24 h measured by a colorimetric assay (MTT), (0 µg/mL = control). Data are expressed as means ± SD and results are displayed as % control, the control being set to 100%. (*p<0.05).

Figure 2

doi: https://doi.org/10.1371/journal.pone.0088203.g002