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The NRF2-KEAP1 Pathway Is an Early Responsive Gene Network in Arsenic Exposed Lymphoblastoid Cells

Figure 6

The Nrf2-Keap1 regulatory pathway and iAs responsive transcripts.

Known and novel iAs responsive Nrf2 transcripts are shown. Empty circles depict unaffected target transcripts (not differentially expressed in lymphoblastoid cells). Bold and no continuous line circles indicate the level of increased gene expression as identified within this study. Bold line = 2–5 fold, no continuous line = >10. Bold letter depicted novel Nrf2-target genes identify by microarrays.

Figure 6

doi: https://doi.org/10.1371/journal.pone.0088069.g006