KDT501, a Derivative from Hops, Normalizes Glucose Metabolism and Body Weight in Rodent Models of Diabetes
Figure 4
Human subcutaneous adipocyte gene signatures.
Cells were treated with test compounds rosiglitazone (1 µM), telmisartan (10 µM) or KDT501 (25 µM) for 5 days. Gene arrays were performed and the probe sets selected were those with at least a 2-fold change as described in methods. Venn diagram represents up-regulated (A) and down regulated genes (B). KDT501-mediated (probe set 24) 3-way gene-intersection (rosiglitazone, KDT501 and telmisartan) were presented (C). * Probe set values for rosiglitazone and telmisartan are not qualified to include in the figure.