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Computational Study on the Inhibitor Binding Mode and Allosteric Regulation Mechanism in Hepatitis C Virus NS3/4A Protein

Figure 9

Dynamical cross-correlation maps illustrating the correlation of motion between residues in (A) apo, (B) inhibitor bound, (C) apo (truncated) and (D) inhibitor bound (truncated) HCV NS3/4A protein.

The color scale is represented on the right ranging from red to blue: highly positive correlations are in red, highly negative correlations are in blue.

Figure 9

doi: https://doi.org/10.1371/journal.pone.0087077.g009