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Egg-Derived Tri-Peptide IRW Exerts Antihypertensive Effects in Spontaneously Hypertensive Rats

Figure 8

IRW treatment attenuates tissue nitrotyrosine and fibrosis in SHRs.

(A and B) Immunostaining for nitrotyrosine in aortic and kidney sections from untreated and high dose (15mg/Kg BW) IRW treated SHRs. (C and D) Immunostaining for type I collagen in aortic and kidney sections from untreated and high dose (15mg/Kg BW) IRW treated SHRs. Data represented as mean ± SEM from n= 3-4 animals per treatment group. * and *** indicate P<0.05 and P<0.001 respectively, as compared to the untreated group.

Figure 8

doi: https://doi.org/10.1371/journal.pone.0082829.g008