Egg-Derived Tri-Peptide IRW Exerts Antihypertensive Effects in Spontaneously Hypertensive Rats
Figure 5
IRW treatment attenuates inflammatory markers in SHRs.
(A and B) Relative changes in plasma IL-6 and MCP-1 levels in untreated and high dose (15mg/Kg BW) IRW treated SHRs. (C and D) ICAM-1 and VCAM-1 expression, normalized to ß actin in mesenteric artery lysates from untreated and high dose (15mg/Kg BW) IRW treated animals. Data represented as mean ± SEM from n= 4-6 animals per treatment group. *, ** and *** indicate P<0.05, P<0.01 and P<0.001 respectively, as compared to the untreated group.