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Egg-Derived Tri-Peptide IRW Exerts Antihypertensive Effects in Spontaneously Hypertensive Rats

Figure 2

IRW treatment restores the circadian rhythms of BP in SHRs.

(A, B and C) SBP, DBP and MAP (mmHg) values from SHRs left untreated or treated with a low dose (3mg/Kg BW) or high dose (15mg/Kg BW) of IRW were recorded during light and dark cycles over a period of 18 days. (D) 2way ANOVA to demonstrate the effects of IRW (low and high dose) on circadian rhythm in MAP. Data represented as mean ± SEM from n=6 animals per treatment group.

Figure 2

doi: https://doi.org/10.1371/journal.pone.0082829.g002