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A Protocol for Quantifying Lipid Peroxidation in Cellular Systems by F2-Isoprostane Analysis

Figure 1

The chemical structure and mass spectrum of F2-isoprostanes.

(A) Four isomeric classes of F2-isoprostanes are formed as a result of oxidative damage to arachidonic acid. (B) The product ion scan of F2-class-III and F2-class-VI isoprostanes. The ion masses indicated in red were used as MRM transition pairs for the indicated isoprostanes.

Figure 1

doi: https://doi.org/10.1371/journal.pone.0080935.g001