X-Ray Crystal Structure of the Ancestral 3-Ketosteroid Receptor–Progesterone–Mifepristone Complex Shows Mifepristone Bound at the Coactivator Binding Interface
Figure 2
Overall structure of the ancSR2–progesterone–mifepristone complex.
Overall structure of the ancSR2 LBD with bound progesterone and mifepristone shown as green and magenta, respectively with oxygens, colored red. Helices are blue, β-sheets are yellow, loops are white. Figures were generated in PyMol (Schödenger, LLC).