Intramolecular Telomeric G-Quadruplexes Dramatically Inhibit DNA Synthesis by Replicative and Translesion Polymerases, Revealing their Potential to Lead to Genetic Change
Figure 1
A) Structure of a G-quartet in the presence of a monovalent cation (M+). Hydrogen-Hoogsteen bonds are indicated by red dashes. B) An intramolecular G-quadruplex structure, consisting of three planar G-quartets. C) G-quadruplex classifications, based on the number of strands involved.