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Novel Histopathological and Molecular Effects of Natural Compound Pellitorine on Larval Midgut Epithelium and Anal Gills of Aedes aegypti

Figure 8

Transmission electronic micrographs of anal gill regions of third instar Ae. aegypti larvae.

(A) The anal gill of the control larva was surrounded by thick cuticle (CU) and inner surface covered with epithelial layer (EP) having large swelling anal gill cells (AGC) filled with hemolymph. (B) The anal gill of a larva treated with 5 mg/l natural pellitorine showed damaged outer membrane surrounded by a thick cuticle, which led to internal lumen content destruction, particularly degeneration of all anal gill cells.

Figure 8

doi: https://doi.org/10.1371/journal.pone.0080226.g008