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Mapping the Structural and Dynamical Features of Multiple p53 DNA Binding Domains: Insights into Loop 1 Intrinsic Dynamics

Figure 5

The profile of residual flexibility of p53 DBD, as indicated by root mean square fluctuation (RMSF).

The RMSF for all concatenated MD conformers are shown in grey histogram. The RMSFs for extended and recessed L1 conformers are shown in magenta and cyan lines, respectively. Black and grey boxes represent alpha helices and beta sheets, respectively. L1, L2 and L3 are indicated as blue, green and red lines, respectively.

Figure 5

doi: https://doi.org/10.1371/journal.pone.0080221.g005