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New Pyrazolopyrimidine Inhibitors of Protein Kinase D as Potent Anticancer Agents for Prostate Cancer Cells

Figure 4

Synthesis and SAR analysis of 1-NA-PP1 analogs.

A. 4-Zone model for 1-NA-PP1 analog synthesis. B. Synthesis of 1H-pyrazolo[3,4-d]pyrimidines 1.

Figure 4

doi: https://doi.org/10.1371/journal.pone.0075601.g004