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Dietary Oleic Acid Increases M2 Macrophages in the Mesenteric Adipose Tissue

Figure 2

Oleic acid induces M2 macrophage markers in

Arginase-1 (Arg1) and TNFα gene expression fold change from (A) RAW 264.7 macrophages or (B) bone marrow derived macrophages (BMDM) cultured overnight with oleic (OA) or palmitic (PA) acid (500 µM). (N = 3,4) (C) CD206, MGL1 and KLF4 gene expression fold change in RAW 264.7 macrophages following overnight culture in OA (500 µM). (D) Arg1 and CD206 gene expression fold change from RAW 264.7 macrophages cultured in OA (200 µM) and PA (as labeled). Control cells were cultured in BSA and ethanol. (N = 3).

Figure 2

doi: https://doi.org/10.1371/journal.pone.0075147.g002