Sodium Butyrate Induces Growth Inhibition and Apoptosis in Human Prostate Cancer DU145 Cells by Up-Regulation of the Expression of Annexin A1
Figure 3
NaB treatment up-regulates the expression of ANXA1 in DU145 cells.
(A) ANXA1 mRNA expression is detected by qRT-PCR. NaB treatment groups significantly higher than control group (treatment by medium only). (B) Western blot analysis of ANXA1 expression in DU145 cells after NaB treatment. Data are normalized with β-actin values and are expressed as fold changes of β-actin in NaB treated group relative to control. All experiments were repeated at least three times. Data are means ± SEM. (n = 3) (Dunnett’s test, *P<0.05 vs. control).