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Solvent Dependency of the UV-Vis Spectrum of Indenoisoquinolines: Role of Keto-Oxygens as Polarity Interaction Probes

Figure 4

TD-DFT vs. UV-Vis for NSC314622.

Comparison of UV/Vis absorption spectra of the indenoisoquinoline NSC314622 in CCl4 (red line) and in DMSO (black line) with TD-DFT calculated transitions. The inset represents a close-up view of the absorption in the 300–400 nm interval. The TD-DFT transitions (dashed vertical lines), calculated in CCl4 and DMSO using C-PCM, are reported as red and black circles respectively and the wavelength of the transitions are annotated. The OS are all rescaled by a factor of 0.25 in order to permit a direct visual comparison with experimental spectra.

Figure 4

doi: https://doi.org/10.1371/journal.pone.0073881.g004