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Eicosapentaenoic Acid Enhances Heat Stress-Impaired Intestinal Epithelial Barrier Function in Caco-2 Cells

Figure 5

EPA decreases paracellular permeability induced by heat stress by determining HRP flux.

Caco-2 monolayers were treated with heat at 43°C for 1 h after absence (control) or presence of PUFAs for 96 h. HRP transport in the basolateral chambers was calculated as a percentage of added HRP after heat stress,. Values are means ± SD. N = 6 per group. * P<0.05, ** P<0.01 compared with 37°C group. # P<0.05, # #P<0.01 compared with 43°C group.

Figure 5

doi: https://doi.org/10.1371/journal.pone.0073571.g005