Re-Imagining the Future: Repetition Decreases Hippocampal Involvement in Future Simulation
Figure 2
Results from contrast analyses.
(A) Regions from the interaction analysis in which fMRI signal decreased across repetitions for the future condition only: right hippocampus (xyz 22 −10 −14, top panel) and left inferior frontal gyrus (−36 28 −16, bottom panel), and associated percent signal change data for future and control conditions (First = FirstFuture and time1Control conditions; Second = SecondFuture; Third = ThirdFuture and time2Control conditions). These regions were also evident in the contrast of First>Second>Third (see Table 3). (B) Regions from the interaction analysis in which fMRI signal increased across repetitions for the future condition only: right precuneus (14 −64 38, top panel) and left anterior prefrontal cortex (−30 52 20, bottom panel) with associated percent signal change data. These regions were also evident in the contrast of Third>Second>First (see Table 3). Activity is shown at puncorrected <.0001 overlaid on a standard anatomical template; all peak activations survived a corrected threshold of pFWE <.05; see Table 3. Note that error bars are not included as these plots are for descriptive purposes only [54].