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New Developments and Applications of the MP2RAGE Sequence - Focusing the Contrast and High Spatial Resolution R1 Mapping

Figure 2

Plots of the theoretical relationship between T1 values and MP2RAGE intensity.

(a) MP2RAGE as a function of T1 for the parameters that optimize contrast over all values of T1 present in the brain (dark grey line) and the parameters that optimize contrast for T1 values between those of WM and GM (light grey). The dashed lines represent the variation in intensities when the effective B1+ is ±40% of the nominal value while dark dotted lines show the T1 values for which Protocol A was optimised and light dotted lines show the T1 values for which Protocol B was optimised. (b) Plot of the contrast to noise ratio between successive T1 values (δT1 = 0.05 s) for the different protocols as a function of T1. The dashed line shows the corrected CNR when the effect of the Partial Fourier in protocol B is taken into account.

Figure 2

doi: https://doi.org/10.1371/journal.pone.0069294.g002