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Identification of Highly Selective and Potent Histone Deacetylase 3 Inhibitors Using Click Chemistry-Based Combinatorial Fragment Assembly

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Growth inhibition of colon cancer HCT116 cells and prostate cancer PC3 cells by vorinostat (3), compound 1, T247, and T326a.

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doi: https://doi.org/10.1371/journal.pone.0068669.t003