Inhibition of GSK 3β Activity Is Associated with Excessive EZH2 Expression and Enhanced Tumour Invasion in Nasopharyngeal Carcinoma
Figure 1
Expression of p-GSK3β (Ser9) and EZH2 in NPC tissues and normal controls.
(A) Representative immunohistochemical staining results of EZH2 and p-GSK3β (Ser9) in NPC and control tissues; (B) The mean number of EZH2 positive cells is greater in NPC tissues than in normal controls; (C) The mean number of p-GSK3β positive cells is greater in NPC tissues than in normal controls; (D) Coincident high or low EZH2 and p-GSK3β (Ser9) immunohistochemical staining in 2 representative NPC tissues; (E) Immunoreactivity of EZH2 is positively associated with p-GSK3β (Ser9) immunoreactivity in NPC tissues; (F) Immunoreactivity of EZH2 is positively associated with higher stage of NPC.