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Identification of Novel Stress Granule Components That Are Involved in Nuclear Transport

Figure 6

Heat shock targets importin-β1, but not CAS, to SGs.

In heat-shocked HeLa cells, importin-β1, CAS and HuR (A) or G3BP1 (B) were detected by indirect immunofluorescence. DNA was stained with DAPI; size bar is 20 µm. Magnified views (500×) of SG-containing regions are depicted for stressed cells.

Figure 6

doi: https://doi.org/10.1371/journal.pone.0068356.g006