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Identification of Novel Stress Granule Components That Are Involved in Nuclear Transport

Figure 4

Importin-β1, but not CAS, binds to SGs in response to oxidative stress.

HeLa cells treated with DEM or arsenite were stained with antibodies against the carrier importin-β1 or CAS. Co-staining was performed with the SG marker HuR; nuclei were detected with DAPI. Size bar is 20 µm; SG-containing areas (white squares) are magnified 500×.

Figure 4

doi: https://doi.org/10.1371/journal.pone.0068356.g004