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Evidence for Glutamate as a Neuroglial Transmitter within Sensory Ganglia

Figure 9

Relation between injured neurons and change in glutamate expression.

Seven days following CCI of the inferior orbital nerve many neurons show increased levels of glutamate immunosignal (A, arrows and see Figure 8). Not all these cells are double labeled for ATF3 (B, arrows) a marker of neuronal injury. The neurons indicated with arrowheads are also above threshold but not ATF3 immuno positive. This is not due to the nucleus being out of the plane of section as DAPI staining (C, arrowheads) shows nuclei are present. Scale bar = 30 µm.

Figure 9

doi: https://doi.org/10.1371/journal.pone.0068312.g009