Evidence for Glutamate as a Neuroglial Transmitter within Sensory Ganglia
Figure 5
Summary data of calcium imaging experiment on glutamate receptor activation.
Effects of each agonist were significantly blocked in the presence of their respective antagonists (A, SGCs; B, neurons) in calcium imaging experiments. Pre-treatment of the selective appropriate antagonist, resulted in a reduction in activation by the agonist of both neurons and SGCs. Cell numbers used in this summary bar graph (neuron/SGC): AMPA (25/35), NMDA (12/9), DHPG (20/5) and KA (11/22). Each agonist used 3–4 cultures from 2–3 animals. Each column represents the mean ± S.E.M. ***, P<0.001; **P<0.01.