Plant Derived Aporphinic Alkaloid S-(+)-Dicentrine Induces Antinociceptive Effect in Both Acute and Chronic Inflammatory Pain Models: Evidence for a Role of TRPA1 Channels
Figure 3
Effect of S-(+)-dicentrine (DCTN, 100 mg/kg, p.o.) on thermal hypersensitivity to cold (panel A) and heat (panel B), induced by CFA 80%.
Each bar represents the mean ± S.E.M. of 10 animals. Significance levels are indicated by *p<0.05, **p<0.01 and ***p<0.001 when compared to control group and #p<0.05 and ##p<0.01 when compared to the CFA i.pl. group (one-way anova and Student-Newman-Keuls post hoc test).