Structural Insights into Clostridium perfringens Delta Toxin Pore Formation
Figure 4
C. perfringens Delta toxin structure surface from the side (A) and from the bottom of the rim domain (B).
Aliphatic residues (Ala, Val, Ile, Leu, Met) are in salmon and aromatic residues (Phe, Trp, Typ) are in red. Glycerol molecules are shown as grey sticks. In C, a cartoon representation of the glycerol molecules binding region of C. perfringens Delta toxin in cyan superposed with S. aureus LukF in lemon (PDB ID: 3LKF; [19]) and LukF-PV in pink (PDB ID: 1PVL; [20]). In D, the glycerol molecule binding region of Delta toxin, coloured as for Fig. 1 showing the residues involved in binding glycerol which are shown as lemon sticks.