Anticancer Activity of Amauroderma rude
Figure 5
The effects of Amauroderma rude extracts on breast cancer cell survival and apoptosis.
(a) The breast cancer cell line MDA-MB231 were cultured in normal medium treated with different concentrations of Amauroderma rude extract as indicated for 24 hours. Even at low concentrations, Amauroderma rude extract could effectively induce tumor cell death. Cell counting indicated a significant effect of Amauroderma rude at the concentration of 50 µg/ml (left). n = 3, **p<0.01. Typical photos of cell death are shown (right). (b) MDA-MB231 cells were cultured in normal medium treated with Amauroderma rude extract (400 µg/ml) for different periods of time. Extensive cell death was detected after eight hours of treatment. (c) MDA-MB231 cells were cultured in normal medium treated with different concentrations of Amauroderma rude extract as indicated for or 48 hours, followed by apoptosis assay. Treatment with Amauroderma rude induced apoptosis.