Biosynthesis of Sesquiterpene Lactones in Pyrethrum (Tanacetum cinerariifolium)
Figure 6
Phylogenetic analyses of the germacrene A synthases and oxidases.
A, tree based on the deduced amino acid sequences of the putative pyrethrum germacrene A synthase (TcGAS) and other characterized plant GAS genes. B, tree based on the putative pyrethrum germacrene A oxidase (TcGAO) and costunolide synthase (TcCOS) and other characterized plant GAO and COS genes. The tree was constructed by Neighbour-Joining method using ClustalW2 (http://www.ebi.ac.uk/Tools/msa/clustalw2). The species abbreviations are Ci, Cichorium intybus; Ha, Helianthus annuus; Ls, Lactuca sativa; Tp, Tanacetum parthenium; Tc, Tanacetum cinerariifolium.