Biosynthesis of Sesquiterpene Lactones in Pyrethrum (Tanacetum cinerariifolium)
Figure 1
Simplified scheme for the formation of germacrane, eudesmane and guaiane-type sesquiterpene lactones.
The germacrane skeleton is formed from farnesyl diphosphate (FDP) and undergoes a cyclization reaction to either the guaiane or the eudesmane skeleton [43].