A New Algorithm for Integrated Analysis of miRNA-mRNA Interactions Based on Individual Classification Reveals Insights into Bladder Cancer
Figure 9
Venn diagram of predicted miRNA-mRNA interactions in bladder cancer derived from five different methods of integrative analysis (TaLasso, GenMiR++, Spearman correlation, a Meta analysis approach and our new algorithm CAPE RNA).
Two different collectives were analysed: (A) the entire bladder cancer dataset of normal (n = 8) and tumor samples (n = 16) and (B) only the collective of invasive (n = 8) and non-invasive (n = 8) bladder cancer tumor samples. The Venn diagram illustrates the intersection between the top 500 predicted miRNA-mRNA interactions by each method.