In Silico Study on Binding Specificity of Gonadotropins and Their Receptors: Design of a Novel and Selective Peptidomimetic for Human Follicle Stimulating Hormone Receptor
Figure 9
Pharmacophoric similarity of FSHP and hFSHβ.
The chemical space shared by hFSHβ (cyan sticks) and FSHP (green sticks) is color-coded as explained in the side panel. The interactions with the BSRs (orange sticks) of hFSHR (grey cartoon) are shown in black dotted lines. FSHP shares similar pharmacophoric features and molecular interactions with BSRs of hFSHR as hFSHβ.