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Cancer-Associated Fibroblasts from Hepatocellular Carcinoma Promote Malignant Cell Proliferation by HGF Secretion

Figure 6

The abundance of H-CAFs positively correlated with tumor volume in human HCC samples.

(A) The abundance of H-CAFs was dichotomized into two levels, high density and low density. (B) Tumor volumes of the high-density group (n = 27) were significantly higher than tumor volumes of the low-density group (n = 16, P = 0.006).

Figure 6

doi: https://doi.org/10.1371/journal.pone.0063243.g006