Rosiglitazone Treatment of Type 2 Diabetic db/db Mice Attenuates Urinary Albumin and Angiotensin Converting Enzyme 2 Excretion
Figure 8
Linear regression analysis between urinary ACE2 activity and urinary albumin, plasma glucagon, plasma triglycerides and blood glucose levels.
(A) Association of urinary ACE2 activity and urinary albumin excretion in control, db/db and db/db+rosiglitazone mice before and 4 or 8 weeks after commencement of rosiglitazone treatment. (B) Correlation between plasma glucagon and urinary ACE2 activity in control, db/db and db/db+rosiglitazone mice 8 weeks after commencement of rosiglitazone treatment. (C) Correlation between plasma triglycerides and urinary ACE2 activity in control, db/db and db/db+rosiglitazone mice 8 weeks after commencement of rosiglitazone treatment. (D) Correlation between urinary ACE2 activity and non fasted blood glucose levels in control, db/db and db/db+rosiglitazone mice 8 weeks after commencement of rosiglitazone treatment.