Regulation of Retinoid-Mediated Signaling Involved in Skin Homeostasis by RAR and RXR Agonists/Antagonists in Mouse Skin
Figure 4
Retinoid receptor-selective gene regulation.
(a) Retinoid receptor-selective induction of genes with specific roles in retinoid signaling or epidermal barrier homeostasis in skin of mice treated topically with selective agonists for RARα, RARγ or RXR for 14 days. (b) Proposed outcome of selective signaling via RARα-RXR or RARγ-RXR in skin of mice induced by endogenous retinoids, such as all-trans retinoic acid.