CD11b−CD27− NK Cells Are Associated with the Progression of Lung Carcinoma
Figure 5
DN NK cells have proliferative capacity and poor cytotoxic capacity.
(A and C) Two representative flow cytometry analyses of the expression of Annexin-V and 7-AAD (green graphs) relative to isotype-matched controls (red graphs) on the gated DN NK subset versus the CD11b+SP NK subset in TINK cells. (B and D) The frequency of Annexin-V+ and 7-AAD+ NK cells on two gated NK-cell subsets (n = 6; mean±SD). (E) Two representative flow cytometry analyses of Ki-67 expression (green graphs) relative to isotype-matched controls (red graphs) on the gated DN NK subset versus the CD11b+SP NK subset within TINK cells. (F) The frequency of Ki-67+ NK cells on two gated NK-cell subsets (n = 6; mean±SD). (G) Two representative flow cytometry analyses of CD107a expression (green graphs) relative to isotype-matched controls (red graphs) on the gated DN NK subset versus the CD11b+SP NK subset in TINK cells. (H) The frequency of CD107a+ NK cells on two gated NK-cell subsets (n = 6; mean±SD).